Manchester Medical Society

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Stratified Medicine & Telford Memorial Lecture

  • Date: Wednesday 23rd January 2019 from 2.00-5.00 pm (Coffee & Registration from 1.30 pm)
  • Venue: Manchester Dental Education Centre (MANDEC), Higher Cambridge Street, Manchester, M15 6FH
  • Members £0.00
  • Non Members FREE
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MANDEC directions

1.30 pm
Registration & Coffee

2.00 pm
“Psoriasis: towards stratification by phenotype and outcome”
Professor Jonathan Barker, Professor of Medical Dermatology, St John’s Institute of Dermatology, King’s College London

Psoriasis is recognised by WHO as a serious non-communicable disease.  Despite considerable advances in treatment of the disease a number of hurdles remain with achieving better outcomes for patients.  Many would argue that a better understanding of how pathogenetic mechanisms relate to phenotypic variation and how such mechanisms inform treatment would represent a key step forward.  In his talk Professor Barker will expand on these issues and also discuss how such information can be linked to therapeutic drug monitoring.

2.30 pm
“Precision medicine in rheumatoid arthritis – hope or hype?”
Professor Anne Barton, Professor of Rheumatology; Director of the CfMR and Division Lead for the Division of Musculoskeletal and Dermatological Sciences, University of Manchester

Rheumatoid arthritis is a chronic autoimmune condition characterised by synovial joint inflammation and for which a number of treatment options are available.  However, for each treatment, the drug selected will be effective in 6-7 people out of 10.  Currently, selection of treatment is based on trial and error, cost and the time the drugs came to market rather than on rational prescribing.  The 3-4 people who are unlikely to benefit will receive treatment for 3-6 months but will continue to experience disabling joint inflammation and will be exposed to the risk of serious side effects during that time.  As some of the treatments available, this represents a waste of scarce NHS resources.  Management of rheumatoid arthritis, therefore, provides a clear unmet need which could be addressed by precision medicine approaches in which the right treatments are targeted to the right patients.

3.00 pm
“Liquid Biopsies for Cancer Precision Medicine”
Professor Caroline Dive CBE, Deputy Director of the Cancer Research UK Manchester Institute, University of Manchester

3.30 pm

4.00 pm
TELFORD MEMORIAL LECTURE to be given by Professor Sir Munir Pirmohamed, David Weatherall Chair of Medicine and NHS Chair of Pharmacogenetics
“Personalised Medicine: developing a long-term realistic proposition”

5.00 pm

We are grateful to Novartis and Celgene for supporting this meeting